Protocol: A Multiplexed Reporter Assay to Study Effects of Chromatin Context on DNA Double-Strand Break Repair

DNA double-strand breaks (DSBs) can be repaired through various pathways. Understanding how these pathways are regulated is of great interest for cancer research and optimization of gene editing. The local chromatin environment can affect the balance between repair pathways, but this is still poorly...

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Detalles Bibliográficos
Autores principales: Schep, Ruben, Leemans, Christ, Brinkman, Eva K., van Schaik, Tom, van Steensel, Bas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842231/
https://www.ncbi.nlm.nih.gov/pubmed/35173762
http://dx.doi.org/10.3389/fgene.2021.785947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842231/
https://www.ncbi.nlm.nih.gov/pubmed/35173762
http://dx.doi.org/10.3389/fgene.2021.785947

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