Explore the effect of LLY‐283 on the ototoxicity of auditory cells caused by cisplatin: A bioinformatic analysis based on RNA‐seq

BACKGROUND: Cisplatin is a commonly used chemotherapeutic drug in clinics, and long‐term application will lead to hearing impairment. LLY‐283, an inhibitor of PRMT5, has not been reported in deafness. Our study aimed to explore the mechanism of LLY‐283 in hearing impairment. MATERIALS AND METHODS: F...

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Detalles Bibliográficos
Autores principales: Zhao, Bin, Zhang, Dongdong, Sun, Yixin, Lei, Min, Zeng, Peiji, Wang, Yue, Hong, Yongjun, Jiao, Yanchao, Cai, Chengfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842247/
https://www.ncbi.nlm.nih.gov/pubmed/34997776
http://dx.doi.org/10.1002/jcla.24176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842247/
https://www.ncbi.nlm.nih.gov/pubmed/34997776
http://dx.doi.org/10.1002/jcla.24176

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