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Explore the effect of LLY‐283 on the ototoxicity of auditory cells caused by cisplatin: A bioinformatic analysis based on RNA‐seq
BACKGROUND: Cisplatin is a commonly used chemotherapeutic drug in clinics, and long‐term application will lead to hearing impairment. LLY‐283, an inhibitor of PRMT5, has not been reported in deafness. Our study aimed to explore the mechanism of LLY‐283 in hearing impairment. MATERIALS AND METHODS: F...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842247/ https://www.ncbi.nlm.nih.gov/pubmed/34997776 http://dx.doi.org/10.1002/jcla.24176 |