Highly Antiproliferative Latonduine and Indolo[2,3-c]quinoline Derivatives: Complex Formation with Copper(II) Markedly Changes the Kinase Inhibitory Profile

[Image: see text] A series of latonduine and indoloquinoline derivatives HL(1)–HL(8) and their copper(II) complexes (1–8) were synthesized and comprehensively characterized. The structures of five compounds (HL(6), [CuCl(L(1))(DMF)]·DMF, [CuCl(L(2))(CH(3)OH)], [CuCl(L(3))]·0.5H(2)O, and [CuCl(2)(H(2...

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Detalles Bibliográficos
Autores principales: Wittmann, Christopher, Bacher, Felix, Enyedy, Eva A., Dömötör, Orsolya, Spengler, Gabriella, Madejski, Christian, Reynisson, Jóhannes, Arion, Vladimir B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842277/
https://www.ncbi.nlm.nih.gov/pubmed/35104137
http://dx.doi.org/10.1021/acs.jmedchem.1c01740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842277/
https://www.ncbi.nlm.nih.gov/pubmed/35104137
http://dx.doi.org/10.1021/acs.jmedchem.1c01740

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