Non-Clinical Safety Pharmacology Evaluations of Trazpiroben (TAK-906), a Novel Dopamine D(2)/D(3) Selective Receptor Antagonist for the Management of Gastroparesis

BACKGROUND: Gastroparesis is characterized by delayed gastric emptying in the absence of mechanical obstruction. Owing to the potential for serious side effects, current treatments have restrictions on their use and there is a need for novel compounds with favorable safety profiles. Trazpiroben (pre...

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Detalles Bibliográficos
Autores principales: Kreckler, Laura, Osinski, Mark, Williams, Scott, Whiting, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842350/
https://www.ncbi.nlm.nih.gov/pubmed/35173492
http://dx.doi.org/10.2147/JEP.S332715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842350/
https://www.ncbi.nlm.nih.gov/pubmed/35173492
http://dx.doi.org/10.2147/JEP.S332715

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