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A Pilot Application of an iTRAQ-Based Proteomics Screen Estimates the Effects of Cigarette Smokers’ Serum on RPE Cells With AMD High-Risk Alleles

PURPOSE: The aim of this study was to explore whether there are interactions between genetic (ARMS2/HTRA1) and environmental factors (cigarette smoking) in the pathogenesis of age-related macular degeneration (AMD). METHODS: Primary human retinal pigment epithelial (hRPE) cells were obtained from fo...

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Detalles Bibliográficos
Autores principales: Cai, Bincui, Zhang, Zhe, Sun, Shuo, Lin, Tingting, Ke, Yifeng, Li, Zhiqing, Yang, Jin, Li, Xiaorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842534/
https://www.ncbi.nlm.nih.gov/pubmed/35138344
http://dx.doi.org/10.1167/tvst.11.2.15