Genetic variation at mouse and human ribosomal DNA influences associated epigenetic states

BACKGROUND: Ribosomal DNA (rDNA) displays substantial inter-individual genetic variation in human and mouse. A systematic analysis of how this variation impacts epigenetic states and expression of the rDNA has thus far not been performed. RESULTS: Using a combination of long- and short-read sequenci...

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Detalles Bibliográficos
Autores principales: Rodriguez-Algarra, Francisco, Seaborne, Robert A. E., Danson, Amy F., Yildizoglu, Selin, Yoshikawa, Harunori, Law, Pui Pik, Ahmad, Zakaryya, Maudsley, Victoria A., Brew, Ama, Holmes, Nadine, Ochôa, Mateus, Hodgkinson, Alan, Marzi, Sarah J., Pradeepa, Madapura M., Loose, Matthew, Holland, Michelle L., Rakyan, Vardhman K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842540/
https://www.ncbi.nlm.nih.gov/pubmed/35164830
http://dx.doi.org/10.1186/s13059-022-02617-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842540/
https://www.ncbi.nlm.nih.gov/pubmed/35164830
http://dx.doi.org/10.1186/s13059-022-02617-x

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