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Blockade of novel immune checkpoints and new therapeutic combinations to boost antitumor immunity

Immunotherapy has emerged as a promising strategy for boosting antitumoral immunity. Blockade of immune checkpoints (ICs), which regulate the activity of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells has proven clinical benefits. Antibodies targeting CTLA-4, PD-1, and PD-L1 are IC-blo...

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Detalles Bibliográficos
Autores principales: Archilla-Ortega, Adrià, Domuro, Carla, Martin-Liberal, Juan, Muñoz, Purificación
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842574/
https://www.ncbi.nlm.nih.gov/pubmed/35164813
http://dx.doi.org/10.1186/s13046-022-02264-x