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Improvement of the Solubility Amphotericin B Using Olive Oil Nanoemulsion Coated with Chitosan for More Effective Treatment of Zoonotic Cutaneous Leishmaniasis

Amphotericin B (AMB) is a macrolide polyene antibiotic presenting potent anti-cutaneous leishmania activity. Nonetheless, its low water solubility, side effects, and toxicity have limited its therapeutic efficiency. The present study aimed to improve the solubility of AmB in oil-in-water using chito...

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Detalles Bibliográficos
Autores principales: Taghizadeh, Elnaz, Khamesipour, Ali, Khoee, Sepideh, Jaafari, Mahmoud Reza, Hosseini, Seyed Abdollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842604/
https://www.ncbi.nlm.nih.gov/pubmed/35194447
http://dx.doi.org/10.22037/ijpr.2021.115034.15162