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Development and Optimization of Lipid-polymer Hybrid Nanoparticles Containing Melphalan Using Central Composite Design and Its Effect on Ovarian Cancer Cell Lines

The development of controlled-release drug delivery systems has a great potential to improve the efficacy of anticancer drugs. This study aimed to develop and optimize the production of hybrid lipid-polymer nanoparticles (HLPNPs) for the targeted delivery of melphalan anticancer drugs. Response surf...

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Detalles Bibliográficos
Autores principales: Mirnezami, Seyedeh Masoomeh Sadat, Heydarinasab, Amir, Akbarzadehkhyavi, Azim, Adrjmand, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842616/
https://www.ncbi.nlm.nih.gov/pubmed/35194441
http://dx.doi.org/10.22037/ijpr.2021.114575.14923