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An In-silico Approach and Experimental Analysis Combination: Two Strategies for Selecting the third Extracellular Domain (D-EC3) of Human CD133 Marker as a Target for Detection of Cancer Stem Cells

The selection of the appropriate fragment of the cell surface receptors as an antigen is significant for the production of antibodies. CD133, as a suitable biomarker candidate in the cancer stem cells (CSCs), is a glycosylated protein. The antibodies used for analyzing it recognize glycosylated epit...

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Detalles Bibliográficos
Autores principales: Ghani, Sepideh, Yarian, Fatemeh, Bandehpour, Mojgan, Kazemi, Bahram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842621/
https://www.ncbi.nlm.nih.gov/pubmed/35194430
http://dx.doi.org/10.22037/ijpr.2021.115662.15470