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Pigment Epithelium Derived Factor Is Involved in the Late Phase of Osteosarcoma Metastasis by Increasing Extravasation and Cell-Cell Adhesion

Organ tropism of metastatic cells is not well understood. To determine the key factors involved in the selection of a specific organ upon metastasis, we established metastatic cell lines and analyzed their homing to specific tissues. Toward this, 143B osteosarcoma cells were injected intracardially...

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Detalles Bibliográficos
Autores principales: Kuriyama, Sei, Tanaka, Gentaro, Takagane, Kurara, Itoh, Go, Tanaka, Masamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842676/
https://www.ncbi.nlm.nih.gov/pubmed/35174090
http://dx.doi.org/10.3389/fonc.2022.818182