Autophagy-mediated degradation of NOTCH1 intracellular domain controls the epithelial to mesenchymal transition and cancer metastasis

BACKGOUND: Autophagy controls levels of cellular components during normal and stress conditions; thus, it is a pivotal process for the maintenance of cell homeostasis. In cancer, autophagy protects cells from cancerous transformations that can result from genomic instability induced by reactive oxyg...

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Detalles Bibliográficos
Autores principales: Zada, Sahib, Hwang, Jin Seok, Lai, Trang Huyen, Pham, Trang Minh, Ahmed, Mahmoud, Elashkar, Omar, Kim, Wanil, Kim, Deok Ryong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842742/
https://www.ncbi.nlm.nih.gov/pubmed/35164848
http://dx.doi.org/10.1186/s13578-022-00752-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842742/
https://www.ncbi.nlm.nih.gov/pubmed/35164848
http://dx.doi.org/10.1186/s13578-022-00752-3

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