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Autophagy-mediated degradation of NOTCH1 intracellular domain controls the epithelial to mesenchymal transition and cancer metastasis

BACKGOUND: Autophagy controls levels of cellular components during normal and stress conditions; thus, it is a pivotal process for the maintenance of cell homeostasis. In cancer, autophagy protects cells from cancerous transformations that can result from genomic instability induced by reactive oxyg...

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Detalles Bibliográficos
Autores principales:	Zada, Sahib, Hwang, Jin Seok, Lai, Trang Huyen, Pham, Trang Minh, Ahmed, Mahmoud, Elashkar, Omar, Kim, Wanil, Kim, Deok Ryong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842742/ https://www.ncbi.nlm.nih.gov/pubmed/35164848 http://dx.doi.org/10.1186/s13578-022-00752-3

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