Cargando…
Reverse engineering of a mechanistic model of gene expression using metastability and temporal dynamics
Differentiation can be modeled at the single cell level as a stochastic process resulting from the dynamical functioning of an underlying Gene Regulatory Network (GRN), driving stem or progenitor cells to one or many differentiated cell types. Metastability seems inherent to differentiation process...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
IOS Press
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842760/ https://www.ncbi.nlm.nih.gov/pubmed/34897081 http://dx.doi.org/10.3233/ISB-210226 |