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Berberine Inhibits FOXM1 Dependent Transcriptional Regulation of POLE2 and Interferes With the Survival of Lung Adenocarcinoma

Background: Berberine is one of the most interesting and promising natural anticancer drugs. POLE2 is involved in many cellular functions such as DNA replication and is highly expressed in a variety of cancers. However, the specific molecular mechanism of berberine interfering with POLE2 expression...

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Detalles Bibliográficos
Autores principales: Ni, Lulu, Sun, Ping, Fan, Xiaochun, Li, Zhongjie, Ren, Hongli, Li, Jiangan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842794/
https://www.ncbi.nlm.nih.gov/pubmed/35173608
http://dx.doi.org/10.3389/fphar.2021.775514