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A pan-cancer analysis of molecular characteristics and oncogenic role of gasdermins

BACKGROUND: The gasdermins (GSDMs) family is proposed to be pore-forming effector proteins that cause cell membrane permeabilization and pyroptosis. Despite our increasing knowledge of GSDMD, GSDME and GSDMB, the biological functions and the regulation of GSDM expression and activation remain elusiv...

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Detalles Bibliográficos
Autores principales: Mu, Mingchao, Yu, Qiaoling, Zhang, Qin, Guo, Jing, Wang, Xingjie, Sun, Xuejun, Yu, Junhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842873/
https://www.ncbi.nlm.nih.gov/pubmed/35164740
http://dx.doi.org/10.1186/s12935-022-02483-4