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A pan-cancer analysis of molecular characteristics and oncogenic role of gasdermins
BACKGROUND: The gasdermins (GSDMs) family is proposed to be pore-forming effector proteins that cause cell membrane permeabilization and pyroptosis. Despite our increasing knowledge of GSDMD, GSDME and GSDMB, the biological functions and the regulation of GSDM expression and activation remain elusiv...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842873/ https://www.ncbi.nlm.nih.gov/pubmed/35164740 http://dx.doi.org/10.1186/s12935-022-02483-4 |