Topically delivered nitric oxide acts synergistically with an orally administered PDE5 inhibitor in eliciting an erectile response in a rat model of radical prostatectomy.

Patients undergoing radical prostatectomy (RP) have a high incidence of post-operative erectile dysfunction (ED) refractory to treatment by oral phosphodiesterase-type-5-inhibitors (PDE5i). In the present studies, we investigated if a topically applied, nitric oxide microparticle delivery system (NO...

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Detalles Bibliográficos
Autores principales: Tar, Moses T., Friedman, Joel M., Draganski, Andrew, Davies, Kelvin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842897/
https://www.ncbi.nlm.nih.gov/pubmed/34017115
http://dx.doi.org/10.1038/s41443-021-00451-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842897/
https://www.ncbi.nlm.nih.gov/pubmed/34017115
http://dx.doi.org/10.1038/s41443-021-00451-6

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