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The POR rs10954732 polymorphism decreases susceptibility to hepatocellular carcinoma and hepsin as a prognostic biomarker correlated with immune infiltration based on proteomics

The effect of the cytochrome P450 oxidoreductase (POR) rs10954732 (G > A) polymorphism on hepatocellular carcinoma (HCC) susceptibility is unknown. Here we found that A allele carriers showed a 69% decrease in susceptibility to HCC with overall survival (OS) prolonged to 199%, accompanied by lowe...

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Detalles Bibliográficos
Autores principales: Fang, Yan, Yang, Hongming, Hu, Guiming, Lu, Jiakun, Zhou, Jun, Gao, Na, Gu, Yuhan, Zhang, Cunzhen, Qiu, Jinhuan, Guo, Yuanyuan, Zhang, Yunfei, Wen, Qiang, Qiao, Hailing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842912/
https://www.ncbi.nlm.nih.gov/pubmed/35164791
http://dx.doi.org/10.1186/s12967-022-03282-1