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Maternal diabetes-mediated RORA suppression contributes to gastrointestinal symptoms in autism-like mouse offspring

BACKGROUND: Retinoic acid-related orphan receptor alpha (RORA) has been reported to be suppressed in autistic patients and is associated with autism spectrum disorders (ASD), although the potential role and mechanism of RORA on gastrointestinal (GI) symptoms in ASD patients is still not reported. In...

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Detalles Bibliográficos
Autores principales: Xiao, Li, Wang, Min, Zhang, Wanhua, Song, Yuan, Zeng, Jiaying, Li, Huilin, Yu, Hong, Li, Ling, Gao, Pingming, Yao, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842926/
https://www.ncbi.nlm.nih.gov/pubmed/35164690
http://dx.doi.org/10.1186/s12868-022-00693-0