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Role of ammonia for brain abnormal protein glycosylation during the development of hepatitis B virus-related liver diseases

BACKGROUND: Ammonia is the most typical neurotoxin in hepatic encephalopathy (HE), but the underlying pathophysiology between ammonia and aberrant glycosylation in HE remains unknown. RESULTS: Here, we used HBV transgenic mice and astrocytes to present a systems-based study of glycosylation changes...

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Detalles Bibliográficos
Autores principales: Yang, Jiajun, Yin, Mengqi, Hou, Yao, Li, Hao, Guo, Yonghong, Yu, Hanjie, Zhang, Kun, Zhang, Chen, Jia, Liyuan, Zhang, Fan, Li, Xia, Bian, Huijie, Li, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842931/
https://www.ncbi.nlm.nih.gov/pubmed/35164881
http://dx.doi.org/10.1186/s13578-022-00751-4