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Exosomal circLPAR1 functions in colorectal cancer diagnosis and tumorigenesis through suppressing BRD4 via METTL3–eIF3h interaction

BACKGROUND: Exosomes have emerged as vital biomarkers of multiple cancers and contain abundant circular RNAs (circRNAs). However, the potential for exosomal circRNAs to be used in diagnostics and their molecular mechanism of action in colorectal cancer (CRC) remain unclear. METHODS: CRC-specific exo...

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Detalles Bibliográficos
Autores principales: Zheng, Rui, Zhang, Ke, Tan, Shanyue, Gao, Fang, Zhang, Yajie, Xu, Wenxia, Wang, Huabin, Gu, Dongying, Zhu, Lingjun, Li, Shuwei, Chu, Haiyan, Zhang, Zhengdong, Liu, Lingxiang, Du, Mulong, Wang, Meilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842935/
https://www.ncbi.nlm.nih.gov/pubmed/35164758
http://dx.doi.org/10.1186/s12943-021-01471-y