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Long chain fatty acyl-CoA synthetase 1 promotes prostate cancer progression by elevation of lipogenesis and fatty acid beta-oxidation

Fatty acid metabolism is essential for the biogenesis of cellular components and ATP production to sustain proliferation of cancer cells. Long chain fatty acyl-CoA synthetases (ACSLs), a group of rate-limiting enzymes in fatty acid metabolism, catalyze the bioconversion of exogenous or de novo synth...

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Detalles Bibliográficos
Autores principales: Ma, Yongjie, Zha, Junyi, Yang, XiangKun, Li, Qianjin, Zhang, Qingfu, Yin, Amelia, Beharry, Zanna, Huang, Hanwen, Huang, Jiaoti, Bartlett, Michael, Ye, Kaixiong, Yin, Hang, Cai, Houjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842993/
https://www.ncbi.nlm.nih.gov/pubmed/33564069
http://dx.doi.org/10.1038/s41388-021-01667-y