Centromeres are dismantled by foundational meiotic proteins Spo11 and Rec8

Meiotic processes are potentially dangerous to genome stability and could be disastrous if activated in proliferative cells. Here we show that two key meiosis-defining proteins, the double strand break-forming topoisomerase Spo11 and the meiotic cohesin Rec8, can dismantle centromeres. This dismantl...

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Detalles Bibliográficos
Autores principales: Hou, Haitong, Kyriacou, Eftychia, Thadani, Rahul, Klutstein, Michael, Chapman, Joseph H., Cooper, Julia Promisel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843027/
https://www.ncbi.nlm.nih.gov/pubmed/33658710
http://dx.doi.org/10.1038/s41586-021-03279-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843027/
https://www.ncbi.nlm.nih.gov/pubmed/33658710
http://dx.doi.org/10.1038/s41586-021-03279-8

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