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Development of newly synthesised quinazolinone-based CDK2 inhibitors with potent efficacy against melanoma
Inhibiting Cyclin-dependent kinase 2 (CDK2) has been established as a therapeutic strategy for the treatment of many cancers. Accordingly, this study aimed at developing a new set of quinazolinone-based derivatives as CDK2 inhibitors. The new compounds were evaluated for their anticancer activity ag...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843100/ https://www.ncbi.nlm.nih.gov/pubmed/35139719 http://dx.doi.org/10.1080/14756366.2022.2036985 |