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Development of newly synthesised quinazolinone-based CDK2 inhibitors with potent efficacy against melanoma

Inhibiting Cyclin-dependent kinase 2 (CDK2) has been established as a therapeutic strategy for the treatment of many cancers. Accordingly, this study aimed at developing a new set of quinazolinone-based derivatives as CDK2 inhibitors. The new compounds were evaluated for their anticancer activity ag...

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Detalles Bibliográficos
Autores principales: Mohammed, Eman R., Elmasry, Ghada F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843100/
https://www.ncbi.nlm.nih.gov/pubmed/35139719
http://dx.doi.org/10.1080/14756366.2022.2036985

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