Coumarins inhibit η-class carbonic anhydrase from Plasmodium falciparum

Coumarins were discovered to act as inhibitors of α-carbonic anhydrases (CAs, EC 4.2.1.1) after undergoing hydrolysis mediated by the esterase activity of the enzyme to the corresponding 2-hydroxycinnamic acids. Other classes of CAs among the eight currently known do not possess esterase activity or...

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Detalles Bibliográficos
Autores principales: Giovannuzzi, Simone, De Luca, Viviana, Nocentini, Alessio, Capasso, Clemente, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843172/
https://www.ncbi.nlm.nih.gov/pubmed/35139744
http://dx.doi.org/10.1080/14756366.2022.2036986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843172/
https://www.ncbi.nlm.nih.gov/pubmed/35139744
http://dx.doi.org/10.1080/14756366.2022.2036986

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