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Exceptional origin activation revealed by comparative analysis in two laboratory yeast strains

We performed a comparative analysis of replication origin activation by genome-wide single-stranded DNA mapping in two yeast strains challenged by hydroxyurea, an inhibitor of the ribonucleotide reductase. We gained understanding of the impact on origin activation by three factors: S-phase checkpoin...

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Detalles Bibliográficos
Autores principales: Joshi, Ishita, Peng, Jie, Alvino, Gina, Kwan, Elizabeth, Feng, Wenyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843211/
https://www.ncbi.nlm.nih.gov/pubmed/35157703
http://dx.doi.org/10.1371/journal.pone.0263569