Systems analysis of immune responses to attenuated P. falciparum malaria sporozoite vaccination reveals excessive inflammatory signatures correlating with impaired immunity

Immunization with radiation-attenuated sporozoites (RAS) can confer sterilizing protection against malaria, although the mechanisms behind this protection are incompletely understood. We performed a systems biology analysis of samples from the Immunization by Mosquito with Radiation Attenuated Sporo...

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Detalles Bibliográficos
Autores principales: Du, Ying, Hertoghs, Nina, Duffy, Fergal J., Carnes, Jason, McDermott, Suzanne M., Neal, Maxwell L., Schwedhelm, Katharine V., McElrath, M. Juliana, De Rosa, Stephen C., Aitchison, John D., Stuart, Kenneth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843222/
https://www.ncbi.nlm.nih.gov/pubmed/35108339
http://dx.doi.org/10.1371/journal.ppat.1010282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843222/
https://www.ncbi.nlm.nih.gov/pubmed/35108339
http://dx.doi.org/10.1371/journal.ppat.1010282

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