Cargando…
Evolutionary shift from purifying selection towards divergent selection of SARS-CoV2 favors its invasion into multiple human organs
SARS-CoV2 virus is believed to be originated from a closely related bat Coronavirus RaTG13 lineage and uses its key entry-point residues in S1 protein to attach with human ACE2 receptor. SARS-CoV2 could enter human from bat with its poorly developed entry-point residues much before its known appeara...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier B.V.
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843322/ https://www.ncbi.nlm.nih.gov/pubmed/35176330 http://dx.doi.org/10.1016/j.virusres.2022.198712 |