No Detectable Phenytoin Plasma Levels After Topical Phenytoin Cream Application in Chronic Pain: Inferences for Mechanisms of Action

PURPOSE: Topical phenytoin can act as an analgesic in chronic pain, but it is unclear if topical phenytoin gives rise to systemic side effects. Therefore, the aim of this study is: 1) to evaluate safety in chronic pain patients who used topical phenytoin up to 30% applied daily on intact skin and mu...

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Detalles Bibliográficos
Autores principales: Kopsky, David J, Keppel Hesselink, Jan M, Russell, Alan L, Vrancken, Alexander F J E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843343/
https://www.ncbi.nlm.nih.gov/pubmed/35173477
http://dx.doi.org/10.2147/JPR.S345347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843343/
https://www.ncbi.nlm.nih.gov/pubmed/35173477
http://dx.doi.org/10.2147/JPR.S345347

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