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No Detectable Phenytoin Plasma Levels After Topical Phenytoin Cream Application in Chronic Pain: Inferences for Mechanisms of Action
PURPOSE: Topical phenytoin can act as an analgesic in chronic pain, but it is unclear if topical phenytoin gives rise to systemic side effects. Therefore, the aim of this study is: 1) to evaluate safety in chronic pain patients who used topical phenytoin up to 30% applied daily on intact skin and mu...
Autores principales: | Kopsky, David J, Keppel Hesselink, Jan M, Russell, Alan L, Vrancken, Alexander F J E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843343/ https://www.ncbi.nlm.nih.gov/pubmed/35173477 http://dx.doi.org/10.2147/JPR.S345347 |
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