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Alpelisib-Induced Diabetes Mellitus: Case Report, Pharmacodynamics and Management Considerations

INTRODUCTION: Alpelisib is an orally selective PI3K alpha inhibitor recently available for the treatment of advanced breast cancer. PI3K pathway is an intracellular signaling pathway that plays an important role in regulating glucose metabolism. Hyperglycemia is the most common adverse event associa...

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Detalles Bibliográficos
Autores principales: Pla Peris, Begoña, Arranz Martin, Alfonso, Ballesteros García, Anabel, Sebastián-Valles, Fernando, Marazuela Azpiroz, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843667/
https://www.ncbi.nlm.nih.gov/pubmed/35178031
http://dx.doi.org/10.3389/fendo.2022.802612