Androgen receptor signaling promotes Treg suppressive function during allergic airway inflammation

Women have higher prevalence of asthma compared with men. In asthma, allergic airway inflammation is initiated by IL-33 signaling through ST2, leading to increased IL-4, IL-5, and IL-13 production and eosinophil infiltration. Foxp3(+) Tregs suppress and ST2(+) Tregs promote allergic airway inflammat...

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Detalles Bibliográficos
Autores principales: Gandhi, Vivek D., Cephus, Jacqueline-Yvonne, Norlander, Allison E., Chowdhury, Nowrin U., Zhang, Jian, Ceneviva, Zachary J., Tannous, Elie, Polosukhin, Vasiliy V., Putz, Nathan D., Wickersham, Nancy, Singh, Amrit, Ware, Lorraine B., Bastarache, Julie A., Shaver, Ciara M., Chu, Hong Wei, Peebles, R. Stokes, Newcomb, Dawn C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843736/
https://www.ncbi.nlm.nih.gov/pubmed/35025767
http://dx.doi.org/10.1172/JCI153397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843736/
https://www.ncbi.nlm.nih.gov/pubmed/35025767
http://dx.doi.org/10.1172/JCI153397

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