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Embryonic osteocalcin signaling determines lifelong adrenal steroidogenesis and homeostasis in the mouse

Through their ability to regulate gene expression in most organs, glucocorticoid (GC) hormones influence numerous physiological processes and are therefore key regulators of organismal homeostasis. In bone, GC hormones inhibit expression of the hormone Osteocalcin for poorly understood reasons. Here...

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Detalles Bibliográficos
Autores principales: Yadav, Vijay K., Berger, Julian M., Singh, Parminder, Nagarajan, Perumal, Karsenty, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843753/
https://www.ncbi.nlm.nih.gov/pubmed/34905510
http://dx.doi.org/10.1172/JCI153752