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Transcriptomic Mapping of Non-Small Cell Lung Cancer K-RAS p.G12C Mutated Tumors: Identification of Surfaceome Targets and Immunologic Correlates

Targeting K-RAS-mutant non-small cell lung cancer (NSCLC) with novel inhibitors has shown promising results with the recent approval of sotorasib in this indication. However, progression to this agent is expected, as it has previously been observed with other inhibitors. Recently, new immune therape...

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Detalles Bibliográficos
Autores principales: Alcaraz-Sanabria, Ana, Cabañas Morafraile, Esther, Fernández-Hinojal, Gonzalo, Velasco, Guillermo, Pérez-Segura, Pedro, Pandiella, Atanasio, Győrffy, Balázs, Ocaña, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843839/
https://www.ncbi.nlm.nih.gov/pubmed/35178045
http://dx.doi.org/10.3389/fimmu.2021.786069