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Endoplasmic Reticulum Stress: An Emerging Therapeutic Target for Intervertebral Disc Degeneration

Low back pain (LBP) is a global health issue. Intervertebral disc degeneration (IDD) is a major cause of LBP. Although the explicit mechanisms underpinning IDD are unclear, endoplasmic reticulum (ER) stress caused by aberrant unfolded or misfolded proteins may be involved. The accumulation of unfold...

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Detalles Bibliográficos
Autores principales: Wang, Dong, He, Xin, Zheng, Chao, Wang, Chengzhe, Peng, Pandi, Gao, Chu, Xu, Xiaolong, Ma, Yachao, Liu, Mei, Yang, Liu, Luo, Zhuojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843852/
https://www.ncbi.nlm.nih.gov/pubmed/35178406
http://dx.doi.org/10.3389/fcell.2021.819139