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CD27 expression on Treg cells limits immune responses against tumors

ABSTRACT: Regulatory T cells (Tregs) suppress immune responses and thus contribute to immune homeostasis. On the downside, Tregs also limit immune responses against tumors promoting the progression of cancer. Among the many mechanisms implied in Treg-mediated suppression, the inhibition of dendritic...

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Detalles Bibliográficos
Autores principales: Muth, Sabine, Klaric, Annekatrin, Radsak, Markus, Schild, Hansjörg, Probst, Hans Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843905/
https://www.ncbi.nlm.nih.gov/pubmed/34423375
http://dx.doi.org/10.1007/s00109-021-02116-9