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Pharmacological Inhibition of FAK-Pyk2 Pathway Protects Against Organ Damage and Prolongs the Survival of Septic Mice

Sepsis and septic shock are associated with high mortality and are considered one of the major public health concerns. The onset of sepsis is known as a hyper-inflammatory state that contributes to organ failure and mortality. Recent findings suggest a potential role of two non-receptor protein tyro...

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Detalles Bibliográficos
Autores principales: Alves, Gustavo Ferreira, Aimaretti, Eleonora, Einaudi, Giacomo, Mastrocola, Raffaella, de Oliveira, Junior Garcia, Collotta, Debora, Porchietto, Elisa, Aragno, Manuela, Cifani, Carlo, Sordi, Regina, Thiemermann, Christoph, Fernandes, Daniel, Collino, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843946/
https://www.ncbi.nlm.nih.gov/pubmed/35178052
http://dx.doi.org/10.3389/fimmu.2022.837180