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Brain physiome: A concept bridging in vitro 3D brain models and in silico models for predicting drug toxicity in the brain

In the last few decades, adverse reactions to pharmaceuticals have been evaluated using 2D in vitro models and animal models. However, with increasing computational power, and as the key drivers of cellular behavior have been identified, in silico models have emerged. These models are time-efficient...

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Detalles Bibliográficos
Autores principales: Seo, Yoojin, Bang, Seokyoung, Son, Jeongtae, Kim, Dongsup, Jeong, Yong, Kim, Pilnam, Yang, Jihun, Eom, Joon-Ho, Choi, Nakwon, Kim, Hong Nam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843968/
https://www.ncbi.nlm.nih.gov/pubmed/35224297
http://dx.doi.org/10.1016/j.bioactmat.2021.11.009