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Brain physiome: A concept bridging in vitro 3D brain models and in silico models for predicting drug toxicity in the brain
In the last few decades, adverse reactions to pharmaceuticals have been evaluated using 2D in vitro models and animal models. However, with increasing computational power, and as the key drivers of cellular behavior have been identified, in silico models have emerged. These models are time-efficient...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
KeAi Publishing
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843968/ https://www.ncbi.nlm.nih.gov/pubmed/35224297 http://dx.doi.org/10.1016/j.bioactmat.2021.11.009 |