Cargando…

DNAJB8 in small extracellular vesicles promotes Oxaliplatin resistance through TP53/MDR1 pathway in colon cancer

Chemotherapy is one of the most frequently used therapies for the treatment of colon cancer (COAD). However, Oxaliplatin (L-OHP) resistance is a major obstacle to the effective treatment of COAD. Here, we investigated whether DNAJB8, a heat shock protein 40 (HSP40) family protein, could be used for...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Zheng, Li, Yi, Mao, Rui, Zhang, Yu, Wen, Jun, Liu, Qian, Liu, Yanjun, Zhang, Tongtong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844036/
https://www.ncbi.nlm.nih.gov/pubmed/35165262
http://dx.doi.org/10.1038/s41419-022-04599-x