Differential maturation and chaperone dependence of the paralogous protein kinases DYRK1A and DYRK1B

The HSP90/CDC37 chaperone system not only assists the maturation of many protein kinases but also maintains their structural integrity after folding. The interaction of mature kinases with the HSP90/CDC37 complex is governed by the conformational stability of the catalytic domain, while the initial...

Descripción completa

Detalles Bibliográficos
Autores principales: Papenfuss, Marco, Lützow, Svenja, Wilms, Gerrit, Babendreyer, Aaron, Flaßhoff, Maren, Kunick, Conrad, Becker, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844047/
https://www.ncbi.nlm.nih.gov/pubmed/35165364
http://dx.doi.org/10.1038/s41598-022-06423-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844047/
https://www.ncbi.nlm.nih.gov/pubmed/35165364
http://dx.doi.org/10.1038/s41598-022-06423-0

Ejemplares similares