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Differential maturation and chaperone dependence of the paralogous protein kinases DYRK1A and DYRK1B

The HSP90/CDC37 chaperone system not only assists the maturation of many protein kinases but also maintains their structural integrity after folding. The interaction of mature kinases with the HSP90/CDC37 complex is governed by the conformational stability of the catalytic domain, while the initial...

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Detalles Bibliográficos
Autores principales:	Papenfuss, Marco, Lützow, Svenja, Wilms, Gerrit, Babendreyer, Aaron, Flaßhoff, Maren, Kunick, Conrad, Becker, Walter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844047/ https://www.ncbi.nlm.nih.gov/pubmed/35165364 http://dx.doi.org/10.1038/s41598-022-06423-0

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