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Integrated single-cell multiomics analysis reveals novel candidate markers for prognosis in human pancreatic ductal adenocarcinoma

The epigenomic abnormality of pancreatic ductal adenocarcinoma (PDAC) has rarely been investigated due to its strong heterogeneity. Here, we used single-cell multiomics sequencing to simultaneously analyze the DNA methylome, chromatin accessibility and transcriptome in individual tumor cells of PDAC...

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Detalles Bibliográficos
Autores principales: Fan, Xiaoying, Lu, Ping, Wang, Hongwei, Bian, Shuhui, Wu, Xinglong, Zhang, Yu, Liu, Yang, Fu, Danqi, Wen, Lu, Hao, Jihui, Tang, Fuchou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844066/
https://www.ncbi.nlm.nih.gov/pubmed/35165277
http://dx.doi.org/10.1038/s41421-021-00366-y