Cargando…

Integrated single-cell multiomics analysis reveals novel candidate markers for prognosis in human pancreatic ductal adenocarcinoma

The epigenomic abnormality of pancreatic ductal adenocarcinoma (PDAC) has rarely been investigated due to its strong heterogeneity. Here, we used single-cell multiomics sequencing to simultaneously analyze the DNA methylome, chromatin accessibility and transcriptome in individual tumor cells of PDAC...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fan, Xiaoying, Lu, Ping, Wang, Hongwei, Bian, Shuhui, Wu, Xinglong, Zhang, Yu, Liu, Yang, Fu, Danqi, Wen, Lu, Hao, Jihui, Tang, Fuchou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Singapore 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844066/ https://www.ncbi.nlm.nih.gov/pubmed/35165277 http://dx.doi.org/10.1038/s41421-021-00366-y

Ejemplares similares

Integrative single-cell multiomics analyses dissect molecular signatures of intratumoral heterogeneities and differentiation states of human gastric cancer
por: Bian, Shuhui, et al.
Publicado: (2023)

Podocalyxin Is a Marker of Poor Prognosis in Pancreatic Ductal Adenocarcinoma
por: Saukkonen, Kapo, et al.
Publicado: (2015)

Tumoral EHF predicts the efficacy of anti-PD1 therapy in pancreatic ductal adenocarcinoma
por: Liu, Jing, et al.
Publicado: (2019)

Pancreatic Ductal Adenocarcinoma: Relating Biomechanics and Prognosis
por: MacCurtain, Benjamin M., et al.
Publicado: (2021)

Molecular markers associated with perineural invasion in pancreatic ductal adenocarcinoma
por: Zhang, Junfeng, et al.
Publicado: (2020)

Elevated glypican‐1 expression is associated with an unfavorable prognosis in pancreatic ductal adenocarcinoma
por: Lu, Haizhen, et al.
Publicado: (2017)

Possible Molecular Markers for the Diagnosis of Pancreatic Ductal Adenocarcinoma
por: Shen, Quan, et al.
Publicado: (2018)

Expression of signaling adaptor proteins predicts poor prognosis in pancreatic ductal adenocarcinoma
por: Wang, Lili, et al.
Publicado: (2017)

The immune escape signature predicts the prognosis and immunotherapy sensitivity for pancreatic ductal adenocarcinoma
por: Lu, Hao, et al.
Publicado: (2022)

Markers of Bone Metabolism in Patients With Chronic Pancreatitis and Pancreatic Ductal Adenocarcinoma
por: Pezzilli, Raffaele, et al.
Publicado: (2015)

Impact of caveolin-1 expression on prognosis of pancreatic ductal adenocarcinoma
por: Suzuoki, M, et al.
Publicado: (2002)

Tumour buds determine prognosis in resected pancreatic ductal adenocarcinoma
por: Lohneis, Philipp, et al.
Publicado: (2018)

The effects of systemic inflammatory response on prognosis of pancreatic ductal adenocarcinoma
por: Aktekin, Ali, et al.
Publicado: (2019)

Serum Biomarker Panel for Diagnosis and Prognosis of Pancreatic Ductal Adenocarcinomas
por: Mehta, Shreya, et al.
Publicado: (2021)

The enigmatic helicase DHX9 as a candidate prognostic biomarker for resected pancreatic ductal adenocarcinoma
por: Chen, Le-gao, et al.
Publicado: (2022)

Integrative Multiomics Evaluation of IIDH1 Metabolic Enzyme as a Candidate Oncogene That is Correlated with Poor Prognosis and Immune Infiltration in Prostate Adenocarcinoma
por: Wen, Chen-Yueh, et al.
Publicado: (2022)

RNA Binding Proteins as Drivers and Therapeutic Target Candidates in Pancreatic Ductal Adenocarcinoma
por: Glaß, Markus, et al.
Publicado: (2020)

A new staging system for postoperative prognostication in pancreatic ductal adenocarcinoma
por: Liang, Yuexiang, et al.
Publicado: (2023)

Decreased LKB1 predicts poor prognosis in Pancreatic Ductal Adenocarcinoma
por: Yang, Jian-Yu, et al.
Publicado: (2015)

The role of miRNAs in the diagnosis, chemoresistance, and prognosis of pancreatic ductal adenocarcinoma
por: Ren, Le, et al.
Publicado: (2018)

PRSS1 genotype is associated with prognosis in patients with pancreatic ductal adenocarcinoma
por: Wu, Huasheng, et al.
Publicado: (2020)

Significance of frailty in prognosis after surgery in patients with pancreatic ductal adenocarcinoma
por: Yamada, Shinichiro, et al.
Publicado: (2021)

Analysis of Methylation‐driven Genes in Pancreatic Ductal Adenocarcinoma for Predicting Prognosis
por: Zhang, Zihan, et al.
Publicado: (2021)

Corrigendum: Serum Biomarker Panel for Diagnosis and Prognosis of Pancreatic Ductal Adenocarcinomas
por: Mehta, Shreya, et al.
Publicado: (2021)

The genetic landscape of pancreatic head ductal adenocarcinoma in China and prognosis stratification
por: Yang, Yefan, et al.
Publicado: (2022)

The identification of liver metastasis- and prognosis-associated genes in pancreatic ductal adenocarcinoma
por: Luan, Hong, et al.
Publicado: (2022)

The coagulation-related genes for prognosis and tumor microenvironment in pancreatic ductal adenocarcinoma
por: Wang, Di, et al.
Publicado: (2023)

Development and validation of an MRI-radiomics nomogram for the prognosis of pancreatic ductal adenocarcinoma
por: Xu, Xinsen, et al.
Publicado: (2023)

Development and Validation of a Nomogram Based on Nutritional Indicators and Tumor Markers for Prognosis Prediction of Pancreatic Ductal Adenocarcinoma
por: Li, Haoran, et al.
Publicado: (2021)

Oral mycobiota and pancreatic ductal adenocarcinoma
por: Wei, Ailin, et al.
Publicado: (2022)

An Increased Abundance of Tumor-Infiltrating Regulatory T Cells Is Correlated with the Progression and Prognosis of Pancreatic Ductal Adenocarcinoma
por: Tang, Yichen, et al.
Publicado: (2014)

Mimics of pancreatic ductal adenocarcinoma
por: Al-Hawary, Mahmoud M., et al.
Publicado: (2013)

Pancreatic ductal adenocarcinoma staging
por: Al-Hawary, Mahmoud M., et al.
Publicado: (2013)

Syndecans and Pancreatic Ductal Adenocarcinoma
por: Betriu, Nausika, et al.
Publicado: (2021)

Models of pancreatic ductal adenocarcinoma
por: Dennaoui, Rayane, et al.
Publicado: (2021)

PROX1 and β-catenin are prognostic markers in pancreatic ductal adenocarcinoma
por: Saukkonen, Kapo, et al.
Publicado: (2016)

Fibroblasts as a Biological Marker for Curative Resection in Pancreatic Ductal Adenocarcinoma
por: Katsuta, Eriko, et al.
Publicado: (2020)

Importance of triple tumor markers as biomarkers in patients with pancreatic ductal adenocarcinoma
por: Takagi, Tadataka, et al.
Publicado: (2022)

Integrated single-cell multiomics reveals novel immune candidate markers for post-traumatic coagulopathy
por: Zheng, Ping, et al.
Publicado: (2023)

Identification of key pathways and candidate genes in pancreatic ductal adenocarcinoma using bioinformatics analysis
por: He, Yiping, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_m1km2of7cdivmani7143ke5rtc