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Non-enzymatic formation of isoprene and 2-methyl-3-buten-2-ol (2-MBO) by manganese

It has been suggested that isoprene synthesis by isoprene synthase (IspS) proceeds via a substrate-assisted mechanism. The authors observed a non-enzymatic isoprene formation by Mn(2+), which represents the basis of IspS enzyme reaction. Because IspS and many other terpene synthases require Mn(2+) m...

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Detalles Bibliográficos
Autores principales: Oku, Hirosuke, Mutanda, Ishmael, Fukuta, Masakazu, Inafuku, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844067/
https://www.ncbi.nlm.nih.gov/pubmed/35165356
http://dx.doi.org/10.1038/s41598-022-06520-0