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Regulation of P53 signaling in breast cancer by the E3 ubiquitin ligase RNF187

The tumor suppressor P53 plays critical role in preventing cancer. P53 is rarely mutated and remains functional in luminal-type breast cancer(1). According to current knowledge, wild-type P53 function is tightly controlled by posttranslational modifications, such as ubiquitination. Several ubiquitin...

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Detalles Bibliográficos
Autores principales: Li, Xin, Niu, Zhiguo, Sun, Chen, Zhuo, Shu, Yang, Huijie, Yang, Xiao, Liu, Yun, Yan, Cheng, Li, Zhongbo, Cao, Qi, Ji, Guimei, Ding, Yinlu, Zhuang, Ting, Zhu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844070/
https://www.ncbi.nlm.nih.gov/pubmed/35165289
http://dx.doi.org/10.1038/s41419-022-04604-3