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METTL3 overexpression aggravates LPS-induced cellular inflammation in mouse intestinal epithelial cells and DSS-induced IBD in mice

The inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), are chronic inflammatory disorders of the intestine. Dysregulated cytokine secretion and signal transduction mechanisms via intestinal epithelial cells are involved in IBD pathogenesis, in which the tr...

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Detalles Bibliográficos
Autores principales: Yang, Lichao, Wu, Guotao, Wu, Qiang, Peng, Liangxin, Yuan, Lianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844074/
https://www.ncbi.nlm.nih.gov/pubmed/35165276
http://dx.doi.org/10.1038/s41420-022-00849-1