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Tick tock, tick tock: Mouse culture and tissue aging captured by an epigenetic clock

Aging is associated with dramatic changes to DNA methylation (DNAm), although the causes and consequences of such alterations are unknown. Our ability to experimentally uncover mechanisms of epigenetic aging will be greatly enhanced by our ability to study and manipulate these changes using in vitro...

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Detalles Bibliográficos
Autores principales: Minteer, Christopher, Morselli, Marco, Meer, Margarita, Cao, Jian, Higgins‐Chen, Albert, Lang, Sabine M., Pellegrini, Matteo, Yan, Qin, Levine, Morgan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844113/
https://www.ncbi.nlm.nih.gov/pubmed/35104377
http://dx.doi.org/10.1111/acel.13553